To foster cooperation and mutual exchange between the regional consultative processes on migration (RCPs), IOM has been organizing since 2005 Global Meetings of RCP Chairs and Secretariats. The Fifth Global Meeting of RCP Chairs and Secretariats was organized jointly by the League of Arab States and the International Organization for Migration (IOM) on 21–22 October 2015, in Cairo, Egypt. The report summarizes the discussions and key outcomes of the Meeting, which was held under the theme “Exploring Contemporary Migration Challenges: Reflecting on the Outcomes of the 2013 High-level Dialogue on International Migration and Development and the Post-2015 Development Agenda.” The report includes updates from 16 RCPs on their activities in 2013–2015. The thematic topics discussed included the role of RCPs in protecting the human rights of all migrants, addressing forced migration, mixed migration flows, climate change as well as the cross-fertilization between RCPs and the Global Forum on Migration (GFMD) and cooperation between the RCPs and the civil society. The event had a significant focus on the contribution of RCPs to implementing and reviewing the migration-related targets of the recently adopted 2030 Agenda for Sustainable Development.