This report illustrates IOM’s health activities in 2012. Key achievements in three main programmatic areas are presented: Migration Health Assessments and Travel Health Assistance; Health Promotion and Assistance for Migrants; and Migration Health Assistance for Crisis-Affected Populations. The report also highlights two emerging themes in migration and health, namely, mobilizing diaspora health professionals for health systems strengthening; and health of migrants in the post-2015 development goals. This report aptly illustrates IOM’s growing multidimensional migration health activities and global partnerships. Guided by the Resolution on the Health of Migrants adopted by the World Health Assembly in May 2008, the Report demonstrates IOM’s commitment to advance the health of migrants and their families worldwide, and to support IOM Member States in addressing migration health challenges.